What are the visible changes that NMN can bring to you?

2022/01/11

Since nicotinamide mononucleotide (NMN) was found to promote the increase of NAD+ in the body, the scientific research community has continuously studied its anti-aging efficacy, and some even have given it a "longevity medicine". "The good name.
However, whether it is the improvement of NAD+ in the body by NMN, the repair of DNA, and the suppression of signs of aging in related organs, it can be understood that it is a silent change in the body. However, for consumers who take NMN-related health products, changes in the body are often difficult to perceive. If there is an obvious promotion effect on the outside, it is possible to take it for a long time and spontaneous recommendation with reputation.

Judging from the existing academic articles, the two most likely changes after taking NMN-related products are:
(1) Improvement of sleep quality
(2) Recovery of skin quality and densification of hair
(3) Improvement of sleep quality
As early as 2006, scholars Nakahata & Bessho proposed that regular sleep time is of great significance to the healthy aging process. A disordered sleep pattern will not only accelerate the aging of the human body, but also break the regularity of participation in day farming and night rest. The imbalance of all cells and genes leads to the onset of diseases.

Illustration: The human body participates in the regular material work of day farming and night rest
As shown in the figure, NAD+ (nicotinamide adenine dinucleotide) participates in this law as an important component, maintaining the continuous and healthy development of the entire life form. In an in vivo experiment, Nakahata & Bessho found that compared with adult mice, old mice have much less NAD+ in their cells, and their sleep quality is also worse. And because of the decrease in NAD+, the energy that can be used for day-to-day farming and night-breathing is also much less, and the probability of internal organ problems caused by aging has also risen linearly.
Therefore, when we ingest the relevant NMN in our body to promote the increase of NAD+ substances, there will be more substances in our body that can be used for day-to-day farming and night-breathing, and more energy can be provided for our life activities. many.
Many consumers have reported that after taking NMN-related health products, their sleep quality has been significantly improved, especially the symptoms of insomnia have been improved. The reason is the above-mentioned explanation.

Recovery of skin quality and densification of hair
Niacinamide is a very popular ingredient in cosmetics and skin care products, and its whitening and repairing effects are almost mentioned in the product promotion of major brands. As the precursor of NAD+, whether NMN, which has a large amount of anti-aging research, can have a targeted effect on aging skin problems outside the skin is also the focus of scientific research in the past two years.
An in vivo experiment conducted by Dr. Keshav Singh and his colleagues at the University of Alabama at Birmingham showed that when the experimental mice`s mitochondria declined or dysfunctional mutations occurred, the experimental mice would develop skin folds within a few weeks. And large areas of visible hair loss. When the mitochondria of these mice returned to normal, the skin quickly became smooth and the hair became thicker, which was almost indistinguishable from healthy mice of the same age.

Then there will be a problem involved here. What are mitochondria? Why can the improvement of mitochondria make such a big change to the appearance of the mice?
From a biological point of view, the principle of action of mitochondria is mainly to provide kinetic energy for cells, and it is even known as a "miracle of life evolution" in the industry.
Mitochondria are a kind of organelle in the cell, which is about the shape of a short rod; they take in oxygen and "fuel" from the surrounding cell fluid, allowing them to "burn" inside, and the chemical energy used is the cell All the activities that require energy are supplied with energy-just like an engine.
The higher the mitochondrial component of a somatic cell, the greater the kinetic energy it creates, the better the function of the cell, and the better the state of feedback to our external physical signs. What we call wrinkles and hair loss are one of the important signs that related organs are gradually aging.
"Under normal circumstances", after a person is 30 years old, the efficiency of mitochondria begins to decline; by the age of 70, it will drop to half of what it was when you were young. In the past, mitochondrial supplementation was a double obstacle to the lack of pathways and the lack of validation of effectiveness. Next, it is difficult to say that we will intervene at the root of it through external means, but all of this becomes more possible with the deepening of NAD+'s exploration.
In 2019, Professor Kane AE from the Department of Genetics of Harvard Medical School and others found that NMN is an important precursor of NAD+ synthesis in the organism. After it increases the level of NAD+ in the cell, it plays many beneficial effects (such as improving metabolism, protecting cardiovascular, etc.) ) Are all achieved by activating Sirtuins. The Sirtuins studied by Professor Kane A E are just one of the magical mitochondria we have discussed for a long time.
Therefore, by taking NMN to promote more Sirtuins mitochondria to be activated, it is also expected to have a miraculous effect externally.
But at the same time, it should be noted that the current regulations on the classification of NMN in cosmetics are not very complete, and the effect of NMN ingredients for external application also requires more scientific research and exploration data.
However, a series of studies by Dr. Keshav Singh and his colleagues also convinced us that in the near future, another shocking high-tech will emerge in our skin care and hair care industry.

In fact, having said so much, I still want to say at the end that the core function of NAD+ is to provide our human body with more energy sources for healthy life. It has been studied by many researchers and focused more on How to use NMN more efficiently to create a more perfect and energetic future society for us. As for the performance of the external appearance described above, it should be said that it varies from person to person to be more accurate at this stage, rather than blindly pushing its superstition to the height of a "longevity medicine".

I hope we can all have more time to enjoy this wonderful world with the advancement of technology.
To provide the industry and the people who need us with the most high-quality raw materials in the NMN industry.